10 exam-style questions with answers and explanations, straight from our 1,037-question bank. Tap an answer to check yourself. When you're ready, take the scored version in the free practice test.
The CPHON exam has 165 questions and runs 3 hours.
These 10 free CPHON questions are organized by exam domain, so you can see how each part of the Certified Pediatric Hematology Oncology Nurse blueprint is tested. Reveal the answer and explanation under each question.
A nurse is caring for a 3-year-old newly diagnosed with a Wilms tumor. Which intervention is MOST important to include in the plan of care?
Correct answer: D - Post a sign at the bedside that the abdomen should not be palpated
A nurse is preparing to administer intravenous vincristine to a child with a brain tumor. The pharmacy has dispensed the vincristine in a syringe. What is the nurse's BEST action?
Correct answer: D - Return it to pharmacy to be dispensed in a minibag before giving it
During peripheral IV administration of vincristine, the site becomes swollen and the nurse can no longer obtain a blood return. After stopping the infusion and aspirating residual drug from the catheter, which intervention is appropriate for this vesicant?
Correct answer: A - Apply a warm compress and administer hyaluronidase
A child is scheduled to receive doxorubicin as part of a treatment protocol. Because of this agent's most significant dose-limiting toxicity, which baseline assessment is MOST important before therapy begins?
Correct answer: A - Echocardiogram to assess cardiac function
A 6-year-old receiving maintenance chemotherapy for acute lymphoblastic leukemia has a CBC showing WBC 2,000/mm3 with a differential of 20% segmented neutrophils, 5% bands, 60% lymphocytes, and 15% monocytes. What is the child's absolute neutrophil count (ANC), and how should the nurse classify it?
Correct answer: C - 500/mm3 - severe neutropenia
A child undergoing chemotherapy has a platelet count of 18,000/mm3. Which nursing intervention is MOST appropriate?
Correct answer: D - Avoid rectal temperatures, suppositories, and intramuscular injections
A child with an absolute neutrophil count of 180/mm3 develops a single oral temperature of 38.7C (101.7F) at home and is brought to the clinic. Which intervention takes PRIORITY?
Correct answer: B - Obtain blood cultures and begin empiric broad-spectrum antibiotics
A child newly diagnosed with Burkitt lymphoma is started on induction chemotherapy. Which set of laboratory findings is MOST consistent with tumor lysis syndrome?
Correct answer: C - High potassium, high phosphate, low calcium, high uric acid
An 8-year-old with sickle cell disease admitted for a vaso-occlusive crisis develops a new fever, chest pain, cough, and an oxygen saturation of 88%. A chest radiograph shows a new pulmonary infiltrate. Which complication should the nurse suspect?
Correct answer: B - Acute chest syndrome
A child with a central nervous system tumor develops a serum sodium of 122 mEq/L, low serum osmolality, concentrated urine, and weight gain without edema. Which condition does this represent, and what is the primary management?
Correct answer: C - Syndrome of inappropriate antidiuretic hormone; restrict fluids
The CPHON exam also covers these domains. Drill them in the full free practice test:
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